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KIDNEY DISEASE



A common disease affecting older pets is Chronic renal failure (CRF).

Clinical signs that can be associated with kidney disease are:

  • Increased thirst
  • Increased urination
  • Decreased appetite
  • Hair coat flakey and rough in appearance
  • Thin
  • Weight Loss
  • Weakness in back legs
  • Mouth odor
  • Vomiting
  • Diarrhea
  • Inappropriate urination or accidents in house

Subtle changes of increased thirst and increased urination may be the first signs of a problem.

 

The kidneys have 3 basic functions:

1)       remove waste

2)       regulate in’s and out’s of the body (electrolytes, water, minerals, etc)

3)       hormone production (i.e. erythropoietin for red blood cell formation and 1,25-dihydroxycholecalciferol for bone and parathyroid)

 

As these 3 kidney functions are lost, the pet may become dehydrated (despite drinking lots of water), anemic (pale gums, weakness) and develop  gastrointestinal problems (nausea, vomiting, decreased appetite, soft stool, foul mouth odor).  However, we prefer to diagnose a kidney problem long before your pet develops such severe clinical signs.

 

Kidney disease patients can survive for many months or years, and with a good quality of life if the problem is diagnosed and treated early.

 

Early kidney disease can be detected with an 

  • Annual blood screen and
  • Urinalysis.

THE POWER OF GOLD!

 

Analyzing the urine is an easy way to determine if early urinary tract problems are present. Abnormal findings may include:

  • Dilute urine- suggesting loss of kidney cell function
  • Protein loss- suggesting leaky vessels or tubules
  • White Blood Cells- suggesting infection or inflammation
  • Crystals or Excess mineral content- suggesting inappropriate diet or infection

A urine analysis is highly recommended in older pets since they are more susceptible to developing urinary tract infections. Such an infection can migrate to the kidneys and subsequently cause damage to the cells of the kidney called nephrons (see case report).

 

Patient Case report:

 

Pet Name: Maui Williams

Date of Birth:  May 1988.

Female spayed Domestic Shorthair cat who resides in a household with 5 other cats and a fairly observant pet owner (Dr. Williams).

 

November, 2001

History: Maui starts showing a rough hair coat and occasional vomiting after eating. 

The vomiting generally occurred within a few hours after eating and about once every 2 or 3 days.

She eats well, is active and otherwise acts normal.

Due to the rough hair coat Dr. Williams brings her to work and checks her urine.

LOTS of white blood cells, bacteria and overall nasty looking bladder infection despite her normal activity and appetite.

 

Urine culture had a positive growth for E.Coli bacteria.

Her bloodwork and blood pressure were normal.

She was started on an antibiotic and kept on the medicine until her urine rechecks showed a normal urine.

 

2002- Annual exam work-up of urine analysis, bloodwork and physical were all within normal limits.

 

2003- No problems noted by owner.

Annual exam blood screening shows a small increase in kidney values (BUN & Creatinine).  Urinalysis was within normal limits except a slightly dilute urine.

 

FYI: To find an elevation in the bloodwork of BUN and Creatinine in a well hydrated pet suggests 75% of the kidney function may be gone. 

Despite this statistic, many patients can live for several years with renal insufficiency. 

 

Maui was placed on a prescription food that is specially formulated to slow the progression of kidney disease (K/D diet).

 

This short story is to emphasize the fact that even the most observant pet owner (Dr. Williams) may overlook a problem.

 

Pets can be very good at hiding pain or discomfort until they REALLY have a severe problem.

 

If you notice something is off with your pet, more often than not you are correct. If your pet is slowing down, consider a check-up with your vet to rule-out an underlying disease that can be treated.

 

Please keep in mind that Old age is not a disease. Appropriate medical care can extend the years and the quality of life for your pet.

 

At the next office visit with your pet, consider the Power of Gold!

 

 


WEBSITES of INTEREST

Pets in the later stages of kidney disease can greatly benefit from fluid therapy to wash out toxins and prevent dehydration.

The following website link demonstrates how to give SQ fluids at home.

Subcutaneous Fluid Administration Guide

 


The following website was created by a pet owner who's cat developed renal failure.  It has a lot of information available on the topic of chronic renal failure.

Feline Chronic Renal Failure Information Center

 


The University of Wisconsin School of Veterinary Medicine has a nice website summarizing treatment options for chronic renal failure in cats as well as Kidney Transplant options.

 

What is chronic renal failure?